| General | CultiSpher is a unique protein-based macroporous
microcarrier. It is manufactured from pharmaceutical grade porcine gelatin via a
process which yields a highly cross-linked gelatin matrix with high mechanical
and thermal stability. When used in cell cultures, cells can attach to both the
external and the internal surfaces of the matrix. The increased surface area of
the matrix together with the protection from stress afforded to the cells in the
interior of the matrix results in enhanced cell production capabilities. An
additional advantage of the product is that the matrix can be dissolved with
proteolytic enzymes resulting in in the harvesting of cells with almost 100%
viability.
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Tissue Engineering |
CultiSpher may also be utilized as an excipient component in preparations of cellular products intended for implantation. Use of the microcarrier in these cellular therapeutic products has been shown to enhance the survival of the implanted cells.
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Distributors |
CultiSpher microcarriers is sold in more than 30 different countries. Contact us for the most convenient supply.
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Conditions of Sale |
CultiSpher microcarriers are delivered exworks (Incoterms 1990). View complete sale conditions 
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CultiSpher-G |
The original macroporous microcarrier suitable for the majority of cell lines.
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CultiSpher-S |
Due to a different crosslinking procedure this microcarrier has a higher thermal and mechanical stability. Cell attachment is also faster. The first microcarrier to try when testing a new cell line.
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Custom-designed |
We have more than 20 years experience in the design and production of microcarriers. Contact us for a discussion on the development of a tailor-made microcarrier for your application.
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Technical specifications |
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| Particle diameter (µm*) | 130-380 | 130-380 | |
| Volume (ml/g dry*) | 12-18 | 10-16 | |
| Density (g/ml*) | 1.04 | 1.04 | |
| Approx. no. of microcarriers ( /g dry) | 1,000,000 | 800,000 | |
| Average pore diameter (µm*) | 20 | 20 | |
| * in PBS | |||
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